{"product_id":"nsj-rq8637-100ug","title":"MAN1 Antibody \/ LEMD3, 100 ug","description":"\u003cp\u003eLEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549649568024,"sku":"RQ8637","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_cfd0f81b-e93b-4fab-90cb-0674b8e366dc.jpg?v=1768301541","url":"https:\/\/danabiosci.com\/products\/nsj-rq8637-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}