{"product_id":"nsj-rq8574-100ug","title":"UBA3 Antibody \/ Ubiquitin-activating enzyme 3 \/ UBE1C, 100 ug","description":"\u003cp\u003eNEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549663953176,"sku":"RQ8574","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_abe2405c-4b0b-4e8a-beea-702d550c4b63.jpg?v=1768301636","url":"https:\/\/danabiosci.com\/products\/nsj-rq8574-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}