{"product_id":"nsj-rq8543-100ug","title":"TRIP10 Antibody \/ CIP4, 100 ug","description":"\u003cp\u003eRequired to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL\/N-WASP which in turn activates the Arp2\/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG\/FASL. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549665755416,"sku":"RQ8543","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7637f617-370a-4054-9797-3d1403fdff7d.jpg?v=1768301683","url":"https:\/\/danabiosci.com\/products\/nsj-rq8543-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}