{"product_id":"nsj-rq7889-100ug","title":"OGDH Antibody \/ 2-oxoglutarate dehydrogenase, 100 ug","description":"\u003cp\u003eAlpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in humans is encoded by the OGDH gene. This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549866557720,"sku":"RQ7889","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9a53c0c5-97c7-4016-8ee9-c278a707df46.jpg?v=1768302724","url":"https:\/\/danabiosci.com\/products\/nsj-rq7889-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}