{"product_id":"nsj-rq7859-100ug","title":"ITGA2B Antibody \/ Integrin alpha 2b, 100 ug","description":"\u003cp\u003eIntegrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549869474072,"sku":"RQ7859","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c8321a92-41ab-4811-b71a-5f196a7b2637.jpg?v=1768302775","url":"https:\/\/danabiosci.com\/products\/nsj-rq7859-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}