{"product_id":"nsj-rq7844-100ug","title":"HBBM Antibody \/ Heparin-binding brain mitogen \/ Pleiotrophin, 100 ug","description":"\u003cp\u003ePleiotrophin (PTN), also known as heparin-binding brain mitogen (HBBM), heparin-binding growth factor 8 (HBGF-8), neurite growth-promoting factor 1 (NEGF1), heparin affinity regulatory peptide (HARP), heparin binding growth associated molecule (HB-GAM) and Osteoblast-specific factor 1 (OSF-1), is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549870686488,"sku":"RQ7844","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6c5ae33f-6f9c-4dde-bcaa-256ac551912d.jpg?v=1768302800","url":"https:\/\/danabiosci.com\/products\/nsj-rq7844-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}