{"product_id":"nsj-rq7828-100ug","title":"Girdin Antibody \/ CCDC88A \/ GIV, 100 ug","description":"\u003cp\u003eGirdin, also called G alpha-interacting vesicle-associated protein (GIV), is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine\/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549874159896,"sku":"RQ7828","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_8e7ddf78-4ee6-45eb-821c-ae0b1825ce28.jpg?v=1768302821","url":"https:\/\/danabiosci.com\/products\/nsj-rq7828-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}