{"product_id":"nsj-rq7666-100ug","title":"SPOP Antibody \/ Speckle-type POZ protein, 100 ug","description":"\u003cp\u003eSpeckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB\/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549892804888,"sku":"RQ7666","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_2b9b8e05-03b4-4575-998b-a5496ac11cc1.jpg?v=1768303048","url":"https:\/\/danabiosci.com\/products\/nsj-rq7666-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}