{"product_id":"nsj-rq7665-100ug","title":"BAF57 Antibody \/ BRG1-associated factor 57 \/ SMARCE1, 100 ug","description":"\u003cp\u003eSWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (SMARCE1), also called BRG1-associated factor 57 (BAF57), is a protein that in humans is encoded by the SMARCE1 gene. The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI\/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI\/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI\/SNF complex. Unlike most of the SWI\/SNF complex proteins, this protein has no yeast counterpart.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549892837656,"sku":"RQ7665","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_43718adf-54ea-43cc-a852-cdd7cce1119d.jpg?v=1768303050","url":"https:\/\/danabiosci.com\/products\/nsj-rq7665-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}