{"product_id":"nsj-rq7635-100ug","title":"hDKIR Antibody \/ C3IP1 \/ KLHL12, 100 ug","description":"\u003cp\u003eKelch-like protein 12, also called CUL3-interacting protein 1 (C3IP1) and DKIR homolog (hDKIR), is a protein that in humans is encoded by the KLHL12 gene. This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549894836504,"sku":"RQ7635","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_8f9b7e57-8998-4934-b301-0f126ff055b0.jpg?v=1768303096","url":"https:\/\/danabiosci.com\/products\/nsj-rq7635-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}