{"product_id":"nsj-rq7587-100ug","title":"ASC1 Antibody \/ TRIP-4, 100 ug","description":"\u003cp\u003eActivating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene. This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549902045464,"sku":"RQ7587","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_ab56b1d7-72c4-4d5c-b5c8-0f10e0b7e16d.jpg?v=1768303170","url":"https:\/\/danabiosci.com\/products\/nsj-rq7587-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}