{"product_id":"nsj-rq7565-100ug","title":"Activated CDC42 kinase 1 Antibody \/ ACK1, 100 ug","description":"\u003cp\u003eActivated CDC42 kinase 1, also known as ACK1, is an enzyme that in humans is encoded by the TNK2 gene. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549903454488,"sku":"RQ7565","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_884c8311-7889-4084-b35b-51497b659735.jpg?v=1768303199","url":"https:\/\/danabiosci.com\/products\/nsj-rq7565-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}