{"product_id":"nsj-rq7493-100ug","title":"TDG Antibody \/ Thymine-DNA glycosylase, 100 ug","description":"\u003cp\u003eG\/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. The protein encoded by this gene belongs to the TDG\/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G\/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C\/T and T\/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51549913547032,"sku":"RQ7493","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_db4acd63-343e-4d19-bc65-8ff283defeb1.jpg?v=1768303320","url":"https:\/\/danabiosci.com\/products\/nsj-rq7493-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}