{"product_id":"nsj-rq6765-100ug","title":"ECD Antibody \/ SGT1, 100 ug","description":"\u003cp\u003eProtein SGT1 is a protein that in humans is encoded by the ECD gene. Regulator of p53\/TP53 stability and function. Inhibits MDM2-mediated degradation of p53\/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550029512984,"sku":"RQ6765","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c9aca984-db04-435e-b3bb-026bbab2493c.jpg?v=1768304415","url":"https:\/\/danabiosci.com\/products\/nsj-rq6765-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}