{"product_id":"nsj-rq6755-100ug","title":"ABCB1 Antibody \/ P Glycoprotein \/ MDR1, 100 ug","description":"\u003cp\u003eP-GP, also called ABCB1, MDR1 and PGY1, is a glycoprotein that in humans is encoded by the ABCB1 gene. It is mapped to 7q21.12. P-GP is a well-characterized ABC-transporter (which transports a wide variety of substrates across extra- and intracellular membranes) of the MDR\/TAP subfamily. It is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent drug efflux pump with broad substrate specificity. P-GP is an ATP-dependent drug efflux pump forxenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood�brain barrier.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550031118616,"sku":"RQ6755","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_03ab60d1-77d0-402e-b967-dd10214cf216.jpg?v=1768304425","url":"https:\/\/danabiosci.com\/products\/nsj-rq6755-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}