{"product_id":"nsj-rq6751-100ug","title":"Pyruvate Kinase Antibody \/ OIP-3 \/ PKM2, 100 ug","description":"\u003cp\u003ePKM (Pyruvate Kinase, Muscle), also known as OIP-3, PK3 and PKM2, is an enzyme that in humans is encoded by the PKM gene. The activity of pyruvate kinase subtype M2 is increased by fructose 1, 6-bisphosphate (Fru-1, 6-P2). By in situ hybridization, Popescu and Cheng (1990) mapped the THBP1 gene to 15q24-q25. Ashizawa et al. (1991) manipulated the intracellular Fru-1, 6-P2 concentration in several mammalian cell lines, including human, by varying the glucose concentration in the media. Using a novel proteomic screen for phosphotyrosine-binding proteins, Christofk et al. (2008) observed that PKM2 binds directly and selectively to tyrosine-phosphorylated peptides.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550031315224,"sku":"RQ6751","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9ec11ba8-d9e5-45b2-95e6-59bd89b4e16d.jpg?v=1768304430","url":"https:\/\/danabiosci.com\/products\/nsj-rq6751-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}