{"product_id":"nsj-rq6658-100ug","title":"Meiotic recombination 11 Antibody \/ MRE11, 100 ug","description":"\u003cp\u003eDouble-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550039539992,"sku":"RQ6658","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_299f9942-3af1-4a88-8b0b-5649f2621043.jpg?v=1768304558","url":"https:\/\/danabiosci.com\/products\/nsj-rq6658-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}