{"product_id":"nsj-rq6582-100ug","title":"NIRF Antibody \/ HRF2, 100 ug","description":"\u003cp\u003eE3 ubiquitin-protein ligase UHRF2 is an enzyme that in humans is encoded by the UHRF2 gene. This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550047240472,"sku":"RQ6582","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_eac0dd82-f987-4bc9-9a83-c71441ef090c.jpg?v=1768304678","url":"https:\/\/danabiosci.com\/products\/nsj-rq6582-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}