{"product_id":"nsj-rq6535-100ug","title":"HSP90AA1 Antibody \/ HSP90 alpha, 100 ug","description":"\u003cp\u003eHeat shock protein HSP 90-alpha is a protein that in humans is encoded by the HSP90AA1 gene. This gene encodes the human stress-inducible 90-kDa heat shock protein alpha (Hsp90A). Complemented by the constitutively expressed paralog Hsp90B which shares over 85% amino acid sequence identity, Hsp90A expression is initiated when a cell experiences proteotoxic stress. Once expressed Hsp90A dimers operate as molecular chaperones that bind and fold other proteins into their functional 3-dimensional structures. This molecular chaperoning ability of Hsp90A is driven by a cycle of structural rearrangements fueled by ATP hydrolysis. Current research on Hsp90A focuses in its role as a drug target due to its interaction with a large number of tumor promoting proteins and its role in cellular stress adaptation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550050156824,"sku":"RQ6535","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_e32479c6-40c6-4fe3-94e7-821c1dde1ac9.jpg?v=1768304744","url":"https:\/\/danabiosci.com\/products\/nsj-rq6535-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}