{"product_id":"nsj-rq6412-100ug","title":"cGAS Antibody \/ cGAMP Synthase, 100 ug","description":"\u003cp\u003ecGAS (cyclic GMP-AMP synthase), also known as MB21D1 (Mab-21 domain containing 1), h-cGAS or C6orf150, is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor. cGAS binds to cytosolic DNA, which leads to cGAMP synthesis and activation of TMEM173, thereby trigger type-I interferon production. Expressed in monocytic cell line THP1, cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550057529624,"sku":"RQ6412","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1f87b8be-e71c-4ec1-b6b4-6b1e2f52e7f1.jpg?v=1768304921","url":"https:\/\/danabiosci.com\/products\/nsj-rq6412-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}