{"product_id":"nsj-rq5767-100ug","title":"TAB2 Antibody, 100 ug","description":"\u003cp\u003eMitogen-activated protein kinase kinase kinase 7-interacting protein 2, also known as TAB2, is an enzyme that in humans is encoded by the MAP3K7IP2 gene. The protein encoded by this gene is an activator of MAP3K7\/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8\/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2 functionally links TAK1 to TRAF6. What's more, TAB2 can act as a sensor for inflammatory signals by serving as a molecular beacon for recruitment of MEKK1(MAP3K1), which in turn mediated dismissal of the NCOR\/HDAC complex and permitted derepression of AR and estrogen receptor target genes.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550107533592,"sku":"RQ5767","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1181727d-1f08-4a29-9bb6-cfd4c0171462.jpg?v=1768305922","url":"https:\/\/danabiosci.com\/products\/nsj-rq5767-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}