{"product_id":"nsj-rq5604-100ug","title":"TNFRSF11B Antibody \/ Osteoprotegerin \/ OPG, 100 ug","description":"\u003cp\u003eTumor necrosis factor receptor superfamily member 11B (TNFRSF11B), also known as OPG, is a protein that in humans is encoded by the TNFRSF11B gene. OPG is a cytokine receptor, and a member of the tumor necrosis factor (TNF) receptor superfamily. By analysis of radiation hybrids, TNFRSF11B gene was mapped to chromosome 8q24. OPG  is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, OPG inhibits nuclear kappa B (NF-?B) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. OPG binding to RANKL on osteoblast\/stromal cells, blocks the RANKL-RANK ligand interaction between osteoblast\/stromal cells and ostepclast precursors.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550121656600,"sku":"RQ5604","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0e6587b3-df07-4b3f-9302-40607e5efc9e.jpg?v=1768306219","url":"https:\/\/danabiosci.com\/products\/nsj-rq5604-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}