{"product_id":"nsj-rq5483-100ul","title":"CD152 Antibody \/ CTLA4, 100 ul","description":"\u003cp\u003eThe CTLA4 gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51550127718680,"sku":"RQ5483","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_358bb58e-c8d0-4512-8379-a1faa66cdf62.jpg?v=1768306418","url":"https:\/\/danabiosci.com\/products\/nsj-rq5483-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}