{"product_id":"nsj-rq5240-100ul","title":"PDHA1 Antibody \/ Pyruvate Dehydrogenase E1 Alpha, 100 ul","description":"\u003cp\u003eThe pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51550138171672,"sku":"RQ5240","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_4fb5002a-cca8-4f09-a640-a11919fe81a2.jpg?v=1768306715","url":"https:\/\/danabiosci.com\/products\/nsj-rq5240-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}