{"product_id":"nsj-rq5205-100ul","title":"MDR1 Antibody \/ P Glycoprotein \/ ABCB1, 100 ul","description":"\u003cp\u003eThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR\/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR\/TAP subfamily. Members of the MDR\/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51550139285784,"sku":"RQ5205","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_62b268db-e674-4ad1-9adb-c57e3f259a8c.jpg?v=1768306739","url":"https:\/\/danabiosci.com\/products\/nsj-rq5205-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}