{"product_id":"nsj-rq4707-100ul","title":"NHERF1 Antibody \/ SLC9A3R1 \/ EBP50, 100 ul","description":"\u003cp\u003eThe SLC9A3R1 gene encodes a sodium\/hydrogen exchanger regulatory cofactor. Na(+)\/H(+) exchange regulatory cofactor NHE-RF1 (also called SLC9A3 regulator 1 and Ezrin-radixin-moesin-binding phosphoprotein 50) interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis\/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [RefSeq]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51550164386072,"sku":"RQ4707","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_b0cb2561-c435-4aae-832b-81654f60deed.jpg?v=1768307455","url":"https:\/\/danabiosci.com\/products\/nsj-rq4707-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}