{"product_id":"nsj-rq4332-100ug","title":"RUNX1T1 Antibody, 100 ug","description":"\u003cp\u003eProtein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene. This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor\/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550181327128,"sku":"RQ4332","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_43d322be-703c-4d18-84f4-fc748041040d.jpg?v=1768307943","url":"https:\/\/danabiosci.com\/products\/nsj-rq4332-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}