{"product_id":"nsj-rq4206-100ug","title":"PERK Antibody \/ EIF2AK3, 100 ug","description":"\u003cp\u003eEukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme that in humans is encoded by the EIF2AK3 gene. The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550185259288,"sku":"RQ4206","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7197fff9-86be-482b-bb04-376f605c403b.jpg?v=1768308064","url":"https:\/\/danabiosci.com\/products\/nsj-rq4206-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}