{"product_id":"nsj-r32473-100ug","title":"BCR Antibody \/ Breakpoint cluster region protein, 100 ug","description":"\u003cp\u003eThe breakpoint cluster region protein (BCR) is a protein that in humans is encoded by the BCR gene. A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine\/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550408474904,"sku":"R32473","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_41375a21-bdc1-4e1a-bea0-da143c0857b5.jpg?v=1768313358","url":"https:\/\/danabiosci.com\/products\/nsj-r32473-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}