{"product_id":"nsj-r32385-100ug","title":"MUC3 Antibody (A\/B), 100 ug","description":"\u003cp\u003eMUC3 consists of two genes, MUC3A and MUC3B, each encoding membrane-bound mucins possessing 2 epidermal growth factor-like domains. The MUC3 gene is mapped to chromosome 7. It was showed that synthetic peptide-mediated upregulation of MUC3 dramatically inhibited adherence of enteropathogenic E. coli or enterohemorrhage E. coli serotype O157:H7 to HT-29 human intestinal epithelial cells. Peptide stimulation altered expression of a number of transcription factors, including upregulation of SP1, CREB1, and CDX2. These transcription factors bound to consensus sites in the MUC3 promoter upon peptide stimulation and likely mediated MUC3 upregulation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550413226264,"sku":"R32385","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_111cccdc-b683-4589-853b-9e82a99f3e88.jpg?v=1768313507","url":"https:\/\/danabiosci.com\/products\/nsj-r32385-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}