{"product_id":"nsj-r32104-100ug","title":"OX40 Antibody \/ CD134, 100 ug","description":"\u003cp\u003eOX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor\/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between the proteins plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550429053208,"sku":"R32104","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_4d392a2e-3506-4afe-944f-0417025f9001.jpg?v=1768313904","url":"https:\/\/danabiosci.com\/products\/nsj-r32104-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}