{"product_id":"nsj-r31826-100ug","title":"TLR5 Antibody, 100 ug","description":"\u003cp\u003eTLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550443143448,"sku":"R31826","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_4c6444e7-b570-4747-ade8-f4d4c0cd70c8.jpg?v=1768314321","url":"https:\/\/danabiosci.com\/products\/nsj-r31826-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}