{"product_id":"nsj-r31721-100ug","title":"DJ-1 Antibody \/ PARK7, 100 ug","description":"\u003cp\u003eParkinson disease 7, also known as Protein deglycase DJ-1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. DJ-1 may function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that DJ-1 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550449762584,"sku":"R31721","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7596bacf-f19f-4549-b807-292f559351e4.jpg?v=1768314457","url":"https:\/\/danabiosci.com\/products\/nsj-r31721-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}