{"product_id":"nsj-r31399-100ug","title":"MKK4 Antibody [MEK4], 100 ug","description":"\u003cp\u003eDual specificity mitogen-activated protein kinase kinase 4 (MAP2K4), also called MEK4, SEK1, JNKK1 and MKK4, is an enzyme that in humans is encoded by the MAP2K4 gene. It is mapped to 17p12. This gene encodes a dual specificity protein kinase that belongs to the Ser\/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8\/JNK1, MAPK9\/JNK2, and MAPK14\/p38, but not MAPK1\/ERK2 or MAPK3\/ERK1. This kinase is phosphorylated, and thus activated by MAP3K1\/MEKK. MAP2K4 was a specific activator of JNK1, JNK2, and p38, and it has been shown to interact with FLNC, MAPK8, MAPK8IP3 and AKT1.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550467981592,"sku":"R31399","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1539b23f-7ed2-475c-8a7d-215d62ac6834.jpg?v=1768314904","url":"https:\/\/danabiosci.com\/products\/nsj-r31399-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}