{"product_id":"nsj-r31393-100ug","title":"IRS-1 Antibody, 100 ug","description":"\u003cp\u003eInsulin receptor substrate 1 is a signalling adapter protein that in humans is encoded by the IRS1 gene. This gene exhibited no intrinsic enzyme activity, and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase. IRS-1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1 (IGF-1) receptors to intracellular pathways PI3K\/Akt and Erk MAP kinase pathways. It also plays important biological function for both metabolic and mitogenic (growth promoting) pathways. In addition to those, IRS-1 is a key regulator of PI3K within malignant cells.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550468112664,"sku":"R31393","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_88bdf3f3-e444-433d-a3f0-19aeb77e8942.jpg?v=1768314908","url":"https:\/\/danabiosci.com\/products\/nsj-r31393-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}