{"product_id":"nsj-r31376-100ug","title":"PIAS1 Antibody, 100 ug","description":"\u003cp\u003eE3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1(signal transducer and activator of transcription-1)] family. It contains a putative zinc-binding motif and a highly acidic region. PIAS1 inhibited STAT1-mediated gene activation in response to interferon when expressed in mammalian cells. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. PIAS1 can also function as a SUMO ligase, or possibly as a tightly bound regulator of it, toward p53.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550468669720,"sku":"R31376","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_66de2c7f-c8bd-484c-849b-a9b3a9b70691.jpg?v=1768314923","url":"https:\/\/danabiosci.com\/products\/nsj-r31376-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}