{"product_id":"nsj-r31275-100ug","title":"Beta Arrestin 1 Antibody, 100 ug","description":"\u003cp\u003eBeta Arrestin 1 is a protein which in humans is encoded by the ARRB1 gene. Members of arrestin\/beta-arrestin protein family are though to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. By fluorescence in situ hybridization,this gene is mapped to 11q13.4. Beta Arrestin 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK\/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550473257240,"sku":"R31275","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_8a18d426-3cea-45ec-88a6-1037332fc6ab.jpg?v=1768315029","url":"https:\/\/danabiosci.com\/products\/nsj-r31275-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}