{"product_id":"nsj-r31269-100ug","title":"TrkA Antibody \/ NTRK1, 100 ug","description":"\u003cp\u003eNeurotrophic tyrosine kinase receptor type 1, also called TrkA, is a protein that in humans is encoded by the NTRK1 gene. The gene encodes the neurotrophic tyrosine kinase-1 receptor and belongs to a family of nerve growth factor receptors whose ligands include neurotrophins. This gene is mapped to 1q23.1. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550473617688,"sku":"R31269","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_6e040088-744c-49ae-87b9-e67ca896c599.jpg?v=1768315035","url":"https:\/\/danabiosci.com\/products\/nsj-r31269-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}