{"product_id":"nsj-r31246-100ug","title":"PLK2 Antibody \/ Polo-like kinase 2, 100 ug","description":"\u003cp\u003ePolo-like kinase 2, also known as SNK, is an enzyme that in humans is encoded by the PLK2 gene. It is a member of the polo family of serine\/threonine protein kinases that have a role in normal cell division. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 5. Polo-like kinase 2 is involved in synaptic plasticity, centriole duplication and G1\/S phase transition. This gene plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signalin: required for overactivity-dependent spine remodeling by phosphorylating the Ras activator RASGRF1 and the Rap inhibitor SIPA1L1 leading to their degradation by the proteasome.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550475125016,"sku":"R31246","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a0220ff6-e73c-486b-9ca8-2fd0adac9d99.jpg?v=1768315067","url":"https:\/\/danabiosci.com\/products\/nsj-r31246-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}