{"product_id":"nsj-r30960-100ug","title":"RIP2 Antibody, 100 ug","description":"\u003cp\u003eReceptor-interacting serine\/threonine-protein kinase 2, also known as CARD3, CARDIAK, RICK, and RIP2, is an enzyme that in humans is encoded by the RIPK2 gene. It has 540-amino acid protein in length. Northern blot analysis revealed that RIPK2 is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. It is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein (RIP) family of serine\/threonine protein kinases. The encoded protein contains a C-terminalcaspase recruitment domain(CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa Band inducer of apoptosis in response to various stimuli, CARDIAK (CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE\/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550488330520,"sku":"R30960","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1b13f3fc-c40e-4fd4-a16c-ee6f801a948f.jpg?v=1768315375","url":"https:\/\/danabiosci.com\/products\/nsj-r30960-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}