{"product_id":"nsj-r30885-100ug","title":"HLA-DM Antibody (beta chain), 100 ug","description":"\u003cp\u003eMajor histocompatibility complex, class II, DM beta, also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLADMB gene. HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chains, both anchored in the membrane. It is located in intracellular vesicles. The protein plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550492524824,"sku":"R30885","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_fda70eb2-f423-424d-85c1-8e31f1bae6bf.jpg?v=1768315479","url":"https:\/\/danabiosci.com\/products\/nsj-r30885-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}