{"product_id":"nsj-r30805-100ug","title":"P-Selectin Antibody \/ SELP \/ CD62P, 100 ug","description":"\u003cp\u003eP-Selectin, also called CD62P, GRMP, and GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation. P-Selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, the protein is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. Expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550495277336,"sku":"R30805","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9b6a39c1-a18e-4c09-8ec6-c04f0c7cb80e.jpg?v=1768315579","url":"https:\/\/danabiosci.com\/products\/nsj-r30805-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}