{"product_id":"nsj-r30614-100ug","title":"ATF4 Antibody, 100 ug","description":"\u003cp\u003eActivating Transcription Factor 4, also know as CREB2, belongs to the large ATF\/CREB family of transcription factors which bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo- and heterodimers to regulate gene transcription. Members of this family share significant sequence similarity within a leucine zipper DNA-binding motif and an adjacent basic region. Unlike CREB, which activates transcription from CRE-containing promoters, CREB2\/ATF4 functions as a specific repressor of CRE-dependent transcription. The transcriptional repressor activity resides within the C-terminal leucine zipper and basic domain region of the ATF4 protein.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550503010584,"sku":"R30614","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_2b2f9117-133f-497c-b40e-3a9814167b92.jpg?v=1768315806","url":"https:\/\/danabiosci.com\/products\/nsj-r30614-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}