{"product_id":"nsj-r30585-100ug","title":"XIAP Antibody, 100 ug","description":"\u003cp\u003eBIRC4, baculoviral IAP repeat-containing protein 4 is also known as X-linked inhibitor of apoptosis protein, or XIAP. The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. XIAP functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550503895320,"sku":"R30585","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0ae68ca0-6de9-4c81-b1b4-511024d537d8.jpg?v=1768315835","url":"https:\/\/danabiosci.com\/products\/nsj-r30585-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}