{"product_id":"nsj-r30511-100ug","title":"Caspase-1 Antibody (p20 subunit), 100 ug","description":"\u003cp\u003eCaspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL-18, and IL-33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas, by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chromosomes. Caspase 1 has been shown to induce cell necrosis or pyroptosis and may function in various developmental stages.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550509269272,"sku":"R30511","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9ca5bb52-9408-4d7b-8c9d-c611977033c4.jpg?v=1768315936","url":"https:\/\/danabiosci.com\/products\/nsj-r30511-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}