{"product_id":"nsj-r30365-100ug","title":"Anti-Caspase-8 Antibody (large subunit), 100 ug","description":"\u003cp\u003eMost upstream protease of the activation cascade of caspases responsible for the TNFRSF6\/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases including CASP3\/4\/6\/7\/9\/10. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550516838680,"sku":"R30365","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_238847ba-0891-440b-bccf-f5442fd84d37.jpg?v=1768316066","url":"https:\/\/danabiosci.com\/products\/nsj-r30365-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}