{"product_id":"nsj-r30048-100ug","title":"MAP Kinase Antibody, Activated (Diphosphorylated ERK-1\u00262), 100 ug","description":"\u003cp\u003eIn mammalian cells, a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein(MAP) kinase pathways. The central core of each MAP kinase(MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase(MAPKKK) phosphorylates and activates a specific MAPK kinase(MAPKK), which then activates a specific MAPK. Mek1\/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ug","offer_id":51550526931224,"sku":"R30048","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_89a2eda2-3379-4d60-8b9f-a6345200e30f.jpg?v=1768316364","url":"https:\/\/danabiosci.com\/products\/nsj-r30048-100ug","provider":"Dana Bioscience","version":"1.0","type":"link"}