{"product_id":"nsj-n1067-25ug","title":"SIN1 Antibody \/ SAPK interacting protein 1 \/ MAPKAP1, 25 ug","description":"\u003cp\u003emTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86\/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"25 ug","offer_id":51550561534232,"sku":"N1067-25UG","price":225.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_ad618ec5-f7e8-4151-8b2e-f5adad244dfe.jpg?v=1768317298","url":"https:\/\/danabiosci.com\/products\/nsj-n1067-25ug","provider":"Dana Bioscience","version":"1.0","type":"link"}