{"product_id":"nsj-fy12715-100ul","title":"INMT Antibody \/ TEMT, 100 ul","description":"\u003cp\u003eINMT antibody detects indolethylamine N methyltransferase, also known as TEMT, encoded by the INMT gene. INMT is a cytosolic enzyme that catalyzes the N methylation of tryptamine and other indolethylamines, producing N N dimethyltryptamine and related metabolites. This activity places INMT in pathways regulating biogenic amine metabolism, neurotransmitter balance, and endogenous hallucinogen production. INMT is expressed in liver, lung, brain, and peripheral tissues, suggesting roles in both metabolic clearance and neuroregulation.\u003cbr\u003e\u003cbr\u003eINMT antibody is widely applied in neurobiology, pharmacology, and metabolism research. INMT contributes to serotonin and tryptamine metabolism and has been proposed as the enzyme responsible for biosynthesis of endogenous dimethyltryptamine in mammals. By detecting INMT, researchers can examine its distribution, activity, and regulation in diverse tissues.\u003cbr\u003e\u003cbr\u003e Western blotting with INMT antibody detects enzyme expression in liver and brain samples. Immunohistochemistry maps expression in neuronal and peripheral tissues, while immunofluorescence highlights cytoplasmic localization within cells. These approaches provide powerful tools for characterizing INMT biology.\u003cbr\u003e\u003cbr\u003eINMT has clinical and pharmacological significance. Altered expression has been linked to pulmonary hypertension, schizophrenia, and other neuropsychiatric conditions. Genetic polymorphisms in INMT influence enzyme activity and metabolic profiles. By applying INMT antibody, scientists can explore how changes in tryptamine metabolism contribute to disease and therapeutic response.\u003cbr\u003e\u003cbr\u003eINMT also participates in xenobiotic metabolism by methylating exogenous compounds. Its role in detoxification pathways expands its relevance to pharmacology and toxicology. INMT antibody supports studies into how methyltransferases regulate chemical balance in the body.\u003cbr\u003e\u003cbr\u003eResearch continues to evaluate INMT in neurological function, where dimethyltryptamine has been implicated in altered states of consciousness and potential therapeutic applications. Investigating INMT expression with antibody based methods provides insights into both fundamental biology and emerging areas of translational research.\u003cbr\u003e\u003cbr\u003eINMT antibody from NSJ Bioreagents provides reliable specificity for detecting indolethylamine N methyltransferase. Its performance across assays ensures accurate results in metabolism, neuroscience, and pharmacology.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51552360726808,"sku":"FY12715","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_983d5434-a39a-459d-9abf-3b1c7f288904.jpg?v=1768353636","url":"https:\/\/danabiosci.com\/products\/nsj-fy12715-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}