{"product_id":"nsj-fy12608-100ul","title":"TIMM22 Antibody \/ Translocase of inner mitochondrial membrane 22, 100 ul","description":"\u003cp\u003eTIMM22 antibody detects translocase of inner mitochondrial membrane 22, a mitochondrial import protein encoded by the TIMM22 gene. TIMM22 is part of the TIM22 complex, which mediates insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. It recognizes hydrophobic precursor proteins delivered by the small TIM chaperone complex and inserts them into the inner membrane in an energy-dependent process. Through this activity, TIMM22 ensures proper biogenesis of mitochondrial carriers and maintenance of energy metabolism.\u003cbr\u003e\u003cbr\u003eTIMM22 antibody is widely applied in mitochondrial biology and protein trafficking research. By detecting TIMM22, scientists can study how mitochondrial import machinery regulates oxidative phosphorylation and cellular energy production. Defects in TIMM22 function lead to impaired assembly of carrier proteins such as ADP\/ATP translocases, disrupting mitochondrial function and cellular homeostasis.\u003cbr\u003e\u003cbr\u003e Western blot assays detect TIMM22 protein in mitochondrial fractions, while immunohistochemistry highlights expression in tissues with high metabolic demand such as muscle, heart, and brain. Immunofluorescence reveals punctate mitochondrial staining, consistent with its localization in the inner membrane. These methods allow precise analysis of mitochondrial import processes.\u003cbr\u003e\u003cbr\u003eMutations in TIMM22 and disruption of mitochondrial protein import are linked to metabolic disorders, neurodegeneration, and cardiomyopathy. By applying TIMM22 antibody, researchers can investigate how defects in import machinery contribute to disease and explore therapeutic strategies to restore mitochondrial function.\u003cbr\u003e\u003cbr\u003eTIMM22 antibody from NSJ Bioreagents provides dependable specificity for studying mitochondrial protein import and energy metabolism. Its strong performance across applications ensures accurate detection of TIMM22 in diverse biological systems.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"100 ul","offer_id":51552375374104,"sku":"FY12608","price":449.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_b87c739b-52a0-48bd-8aaa-423e3e9a466d.jpg?v=1768353844","url":"https:\/\/danabiosci.com\/products\/nsj-fy12608-100ul","provider":"Dana Bioscience","version":"1.0","type":"link"}